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Studies on the genotoxicity of anti-HIV drugs are conducted in many laboratories
IAV infection can induce MAPK phosphatase-5 expression, which has been shown to inhibit IRF3 activation and type I IFN response, thereby enhancing viral replication 77
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In cancer chemotherapy, certain broad-spectrum anticancer drugs exploit the cytotoxicity of ROS to induce cancer cell apoptosis by upregulating intracellular ROS levels(Perillo 2020)
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