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After one month, and based on your glycaemic response and tolerability, your healthcare provider may increase the dose to 10 micrograms twice daily to improve blood glucose control

These vary based on design, chemistry, and intended use

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This DPP-4 inhibitor is contraindicated in this patient group on the basis of the respective cardiovascular safety study that has shown a significant increase of hospitalization for heart failure as secondary endpoint in the saxagliptin arm (63, 66)