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Mechanistically, METTL3 mediates the m6A modification of these SSPrelated genes, while IGF2BP3, functioning as an m6Aspecific reader, inhibits the degradation of their mRNAs
10.1002/jor.1100090406 3 Adjei-SowahE.BenoitD
Sun (2021) a Chinese group working with APP/PS1 amyloid-pathology mice showed restoration of spatial learning with oral dosing (1.442.88 mg/kg, 3 months): neuron and synaptophysin counts rose, astrocyte and microglial activation fell, IL-1 and TNF- dropped and anti-inflammatory IL-10 increased
10.1016/j.ogc.2012.10.002 15
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