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42 A double-blind crossover study from 1973 in patients complaining of tiredness found benefits of hydroxo-B12, 5000 g twice per week i.m
These changes enhance its stability and result in a significantly prolonged half-life of 20-30 hours, compared to the much shorter duration of other IGF-1 versions
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When B12 levels fall below optimal ranges, the integrity of this myelin sheath can become compromised, potentially leading to nerve damage known as peripheral neuropathy
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