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Thus, its role in sepsis may represent a double-edged sword. During sepsis, nearly all cell types undergo metabolic reprogramming
10.1172/JCI116186 129 NESINA (2013)
STAT1 drives M1 microglia activation and neuroinflammation under hypoxia
The link between GSTP and cancer is most obvious in the overexpression of GSTP in many cancers, but it is also supported by the fact that the transformed phenotype of tumor cells is associated with aberrantly regulated kinase signaling pathways and cellular addiction to overexpressed proteins
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