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Impaired FAO in M1 macrophages can result in the aberrant degeneration and accumulation of fatty acids and their derivative lipoproteins, leading to the production of proinflammatory cytokines, including IL-1, which can contribute to the occurrence and development of inflammatory pathologies (148)

Incretins are also responsible for other functions both inside and outside the pancreas

They contribute to the central nervous system (CNS) regulation through dynamic signaling for waste mangement, blood flow modulation, neuroimmune regulation and other processes

Patients should seek medical help for severe or persistent vomiting, signs of dehydration, severe abdominal pain, symptoms of gallbladder disease, allergic reaction, or possible overdose