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Key Treatment Guidelines For optimal outcomes, patients should follow these essential guidelines: Maintain regular resistance training to preserve muscle mass Ensure protein intake of minimum 1.2g per kg of body weight Focus on fiber-rich nutrition protocols Prioritise stress management and sleep optimisation Long-term Considerations While microdosing presents a more conservative approach to GLP-1 therapy, several important factors require ongoing attention

Some practitioners are using them sequentially, starting with semaglutide and switching to tirzepatide if response is suboptimal, similar to how switching between GLP-1 agents works in metabolic contexts

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Stimulate protein synthesis and prevent catabolism or loss of muscle mass