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Although limited randomized clinical trials evidence assessing the effects of GLP-1 receptor agonists on kidney outcomes in diabetic chronic kidney disease patients have been published, FLOW-CKD trial was halted based on interim data for efficacy, and results are awaited

Additional ingredients are present in the same liquid volume but do not affect how you calculate your tirzepatide dose

There may be some evidence, though questionable, that active ingredients like berberine and green tea might curb cravings and reduce appetite a bit , but the effects are not dramatic enough for this to be an FDA-approved strategy. In other words, the patches are likely much ado about nothing

PMID 16314912