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The challenge with oral glutathione supplements is that they are often poorly absorbed

Individuals with Poor Absorption: People with low stomach acid, or those who have had certain surgeries (like gastric bypass), may struggle to absorb B12 from food and would benefit from injections

This means even subcutaneous abdominal injections can support healing at distant injury sites, though local injection produces more concentrated effects

Administration frequency guidelines include: Daily oral dosing for maintenance therapy Weekly or monthly injections for severe deficiencies As-needed dosing based on clinical judgment Guidelines say the dose frequency should match the patients needs and how they respond to treatment