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Canfosfamide Canfosfamide, also known as TLK286, is a GSH analogue activated by GSTP1-1 into a GSH derivative and phosphorodiaminate, an alkylating metabolite that forms covalent linkages with DNA (Fig
Additionally, the peptide might have reactivated the apoptosis pathway, a type of programmed cell death crucial for removing faulty cells, as evidenced by activity in caspases 3 and 7, which are enzymes that play key roles in apoptosis
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