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These pathologies are mediated by microbial metabolites, such as SCFAs, microbial endotoxins, and others, that neurologically act on human brain health directly and indirectly
Male LT2MYC mice were bred and maintained on doxycycline (200 mg/kg doxy chow, BioServ, ad libitum feeding) to suppress oncogene expression
This connects to sleep because oxidative stress in the brain is both a cause and consequence of poor sleep, creating a vicious cycle that neuroprotective peptides may help break
1 Vannelli BG, Barni T, Orlando C, Natali A, Serio M, Balboni GC: Insulin-like growth factor-I (IGF-I) and IGF-I receptor in human testis: an immunohistochemical study
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