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Han HYJ, Hyun CG
Subcutaneous administration in normal and metabolically dysregulated mice significantly inhibits NNMT activity in metabolically active tissues (adipose, liver, muscle), increases systemic NAD+ levels, enhances mitochondrial function, and improves energy metabolism
The ultimate goal is to generate clinical evidence that leads to official changes in treatment guidelines, ensuring that injection frequency is based on patient-reported symptoms and individual clinical response, rather than solely on national blanket protocols
Document daily dose, injection site, and any observed effects to maintain consistency and track tolerance
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