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We also checked the dose-dependent expression of t-p70S6K, p-p70S6K, FOXO3a and p-FOXO3a following exposure to TNF-, with or without L-carnitine, and found that treatment with 1000 g/L L-carnitine increased the protein expression levels of p-FOXO3a, t-p70S6K and p-p70S6K and decreased the level of FOXO3a (Fig

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Elabela alleviates ferroptosis, myocardial remodeling, fibrosis and heart dysfunction in hypertensive mice by modulating the IL-6/STAT3/GPX4 signaling